Your pain may be improved immediately after the injection from the local anesthetic. Once the numbing medicine wears off, your pain may return. It is possible that you will have some soreness at the injection site and your pain may worsen for a day or two after the procedure. The medication takes 2-3 days to start having an effect in most people. Using an ice pack applied three or four times a day can help alleviate the discomfort at the injection site. You may take your usual pain medication after the injection. After your sacroiliac joint injection treatment, you will notice instant relief due to the local anesthetic injected during treatment. Although this will fade within a few hours, the medication should take effect in a few days. At this point, you can expect pain relief that lasts much longer, from anywhere between a few weeks and several months. The duration of the results will vary by patient, but we can help you determine the kind of results you can expect during your initial visit.